Bifidobacterium as an oral delivery carrier of oxyntomodulin for obesity therapy: inhibitory effects on food intake and body weight in overweight mice

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The effects of morphine and nicotine co-administration on body weight, food intake and appetite-regulating peptides in rats

Previous studies in humans and animals have reported that nicotine administration decreases body weightand caloric intake. Opiate and cigarette have been used concomitantly as drug abuse. The aim of the present study was, therefore, to analyze the effect of chronic co-administration of nicotine and morphine on food intake, body weight and on some feeding-associated peptides. All experiments wer...

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Oxyntomodulin (OXM) is a circulating gut hormone released post prandially from cells of the gastrointestinal mucosa. Given intracerebroventricularly to rats, it inhibits food intake and promotes weight loss. Here we report that peripheral (ip) administration of OXM dose-dependently inhibited both fast-induced and dark-phase food intake without delaying gastric emptying. Peripheral OXM administr...

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ژورنال

عنوان ژورنال: International Journal of Obesity

سال: 2010

ISSN: 0307-0565,1476-5497

DOI: 10.1038/ijo.2009.277